Articles
Evidence-based guides, reviewed against primary sources. More are published regularly. Browse by topic for the full picture.

A measured look at the peptide behind the headlines, the animal data, and why human evidence is still thin.

Collagen plus vitamin C before loading is a popular protocol. We weigh the small but growing body of trials.

TB-500, GHK-Cu, and BPC-157 dominate the conversation. We map what is studied, what is sold, and what is legal.

Two evidence-backed loading strategies for stubborn tendon pain, and how to choose between them.

Pain-free is not the same as healed. We cover the strength and capacity benchmarks that lower reinjury risk.

Your body cannot build collagen without the right raw materials. Here is what the nutrition research supports.

The advice has shifted from RICE to PEACE & LOVE. Here is what changed and what it means for the first 72 hours.

Blunting inflammation with ice and NSAIDs can slow the very repair you are trying to speed up.

Anti-inflammatories ease pain but may interfere with tissue remodeling. The timing and dose change the calculus.

Menopause and hormone therapy: what the evidence says
NICE and The Menopause Society converge on the same core picture: hormone therapy is the most effective treatment for hot flushes, and timing, regimen, and route change the risk-benefit balance.

Testosterone therapy: what the evidence actually shows
The Testosterone Trials and the TRAVERSE safety trial show a real but domain-specific benefit (strongest for sexual function, none for vitality), cardiovascular safety with caveats, and clear rules on who should avoid it.

GLP-1 medications for weight loss: what the evidence shows
The STEP 1 and SURMOUNT-1 trial data on semaglutide and tirzepatide: how much weight loss to expect, why they are adjuncts to diet and activity, what happens after stopping, and who should be cautious.

Insulin resistance: what it is and what actually improves it
The Diabetes Prevention Program trial data: an intensive lifestyle intervention cut the incidence of type 2 diabetes by 58% versus placebo, beating metformin. Why fasting glucose, HbA1c, and HOMA-IR are markers, not the disease itself, and where supplement claims fall short.

VO2max and longevity: what cardiorespiratory fitness predicts
A cohort of more than 122,000 adults undergoing exercise treadmill testing found cardiorespiratory fitness among the strongest predictors of survival researchers measured, with no upper limit of benefit.

Sleep and longevity: what the evidence shows
A pooled analysis of more than 1.3 million adults found both short and long sleep duration associated with higher mortality, a U-shaped pattern. We explain why the two ends of that curve do not mean the same thing.

Sciatica: what it is and what actually helps
NICE guidance on nerve-root leg pain: why most sciatica improves with continued activity, when imaging is warranted, and when injections or surgery are actually considered.
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Educational content only. Not a substitute for medical advice.